Index
CRO PROFILECANINE TESTING

Altasciences

A Canadian-origin contract research organization with the largest disclosed CRO canine colony in the United States, wholly owned by Novo Holdings since 2021.

1,931
Dogs on site (2023)
Across 3 U.S. facilities
Source: USDA annual reports FY2023
~1,550
Stated canine capacity
Combined housing across sites
Source: Altasciences facility disclosures
9
Facilities worldwide
U.S., Canada, clinical + preclinical
Source: Company materials
1,800+
Employees
No public revenue disclosure
Source: Company profile

Company Overview

Altasciences traces its origins to Algorithme Pharma, a bioanalytical and clinical pharmacology firm founded around 1992 with roots at the Université de Montréal. The company is headquartered in Laval, Quebec, and operates nine facilities spanning preclinical toxicology, clinical research, and bioanalytical services across the United States and Canada.

The company grew through an aggressive buy-and-build strategy under successive private equity owners. Kilmer Capital Partners held the platform beginning around 2013, adding Vince & Associates (a Kansas City clinical unit). Audax Private Equity acquired the business in 2017 and accelerated acquisitions, including the pivotal purchase of SNBL USA's preclinical operations in Everett, Washington, and expansion into Pennsylvania and Missouri.

In March 2021, Novo Holdings — the investment arm of the Novo Nordisk Foundation — acquired 100% of Altasciences for approximately DKK 2.25 billion (~$340 million). The company is privately held and does not disclose revenue figures. Leadership shifted in February 2026 when Marie-Hélène Raigneau was appointed CEO, with Chris Perkin moving to executive chair.

The Novo Holdings Ownership Chain

The ownership structure creates a direct link between one of the world's largest pharmaceutical companies and a major canine-testing CRO:

1
Novo Nordisk Foundation
Danish industrial foundation; ultimate parent
2
Novo Holdings A/S
100% owned by Foundation; holds 28.1% of Novo Nordisk capital, 76.9% voting rights
3
Altasciences HoldCo A/S
100% owned by Novo Holdings; Danish holding entity
4
Altasciences Group
Operating entity; 9 facilities, 1,800+ employees, canine preclinical colonies
Key Finding
The Novo Nordisk Foundation's 2022 annual report explicitly lists the Altasciences Group among related parties alongside the Novo Nordisk Group. The Foundation states that agreements between related parties are “negotiated on market-based terms.” This creates a structural framework where Novo Nordisk could contract its own sister company for preclinical canine studies — though neither party publicly confirms or denies such arrangements.

Beagle & Canine Operations

Altasciences operates three U.S. preclinical facilities with disclosed canine housing capacity. A fourth site in Sacramento focuses on NHP translational research. USDA annual report data for FY2023 reveals dog populations significantly exceeding stated capacity at some sites:

Auxvasse, MO
Columbia metro
43-R-0122
Capacity: ~700FY2023: 923
Largest site; general toxicology, cardiovascular safety pharmacology
Everett, WA
Seattle metro
91-R-0075
Capacity: ~500FY2023: 530
Former SNBL campus; canines, NHPs, rodents, rabbits
Scott Township, PA
Scranton metro
23-R-0107
Capacity: ~350FY2023: 478
Preclinical tox; added through Audax-era expansion

Combined FY2023 dog count: 1,931 dogs across the three USDA certificates — making Altasciences the largest disclosed CRO canine colony by publicly available data. The Auxvasse facility alone housed 923 dogs against a stated capacity of ~700, a 32% overage.

Study Types & Specializations

General Toxicology
Repeat-dose studies (28-day, 90-day, chronic) in canines for IND-enabling packages
Cardiovascular Safety Pharmacology
hERG-channel telemetry studies in conscious beagles; automated blood sampling
Reproductive & Developmental Toxicology
Segment I-III studies using canine models where regulatory guidance requires non-rodent data
Immunotoxicology & Biologics
Canine immunogenicity and pharmacokinetic studies for biologic drug candidates
Methodology Caveat
Altasciences marketing materials refer to “canines” without disclosing breed composition. Published scientific literature confirms “conscious beagles” in cardiovascular telemetry and automated blood sampling studies at Altasciences facilities. However, the exact proportion of beagles versus other purpose-bred strains is not publicly available. Supplier identity is undisclosed; third-party reporting has alleged connections to specific breeders via Certificates of Veterinary Inspection, but underlying documents require direct verification.

Investigations & USDA Violations

OCT 2024
Official USDA Warning Notice — Everett, WA

USDA APHIS issued a formal warning to Altasciences Preclinical Seattle LLC for an alleged handling violation under 9 C.F.R. § 2.38(f)(1)— the federal standard requiring that handling of animals must be done in a manner that avoids trauma, behavioral stress, physical harm, or unnecessary discomfort. Official warnings represent a step beyond routine inspection citations and signal that APHIS determined a documented violation warranted formal enforcement action.

JUL 2021
4 Critical USDA Citations — Everett, WA

USDA FOIA logs reference an enforcement investigation involving four Animal Welfare Act critical citations for the Everett facility (certificate 91-R-0075). Critical citations are the most severe category in USDA's inspection framework, indicating conditions that directly compromise animal health, welfare, or safety. The specific nature of the violations has not been fully disclosed in publicly available records.

All three dog-housing facilities are marketed as USDA registered and AAALAC accredited. A complete facility-by-facility enforcement timeline would require structured extraction from USDA's Public Search Tool and/or additional FOIA requests beyond what is currently publicly posted.
Data Gap
  • Full USDA inspection reports for all three canine facilities not yet obtained via FOIA
  • Species-specific violation details (whether dogs were the subjects) not confirmed in public records
  • No public disclosure of IACUC composition or independence at any Altasciences facility

The Related-Party Conflict Question

Why This Matters

The ownership chain creates a textbook related-party framework: the Novo Nordisk Foundation controls both Novo Nordisk (76.9% voting rights via Novo Holdings) and Altasciences (100% via Novo Holdings). The Foundation's own financial disclosures list both entities as related parties.

The core question: Does Novo Nordisk contract Altasciences for preclinical canine studies? CRO client engagements are confidential, and neither party publicly itemizes vendor use at the study-provider level. The answer is not publicly confirmed — but the structural conditions for a conflict of interest exist, and the Foundation acknowledges related-party transaction frameworks in its reporting.

If the relationship exists, Novo Nordisk would be directing beagle testing to a laboratory it effectively controls through its parent foundation — raising questions about independent oversight, pricing transparency, and whether welfare standards are subject to genuine arms-length scrutiny.

Key People

Marie-Hélène Raigneau
CEO (effective Feb. 24, 2026)
Succeeded Chris Perkin following Novo Holdings ownership period
Chris Perkin
Executive Chair (2026–present)
Former CEO; led through Novo Holdings acquisition and expansion
Novo Holdings A/S
Parent company (100% owner)
Exercises governance via Altasciences HoldCo A/S

Cross-Border Oversight Context

Altasciences is headquartered in Canada (CCAC voluntary peer-review model) while all dog-housing preclinical operations are U.S.-based under mandatory USDA Animal Welfare Act inspection. This split means the corporate parent operates under voluntary accreditation while its canine testing divisions face federal inspections. Whether uniform welfare standards apply across both regimes is not publicly documented.

Corporate Timeline

~1992Algorithme Pharma founded (predecessor entity, Université de Montréal roots)
~2013Kilmer Capital Partners acquires platform; Vince & Associates clinical unit added
2017Audax Private Equity acquires from Kilmer; aggressive buy-and-build strategy begins
~2018SNBL USA preclinical operations in Everett, WA acquired; becomes Altasciences Preclinical Seattle LLC
2018–2020Expansion into Auxvasse, MO and Scott Township, PA; canine capacity reaches ~1,550
Mar 2021Novo Holdings acquires 100% of Altasciences (~DKK 2.25B / ~$340M) from Audax
Jul 20214 critical USDA citations issued for Everett, WA facility (91-R-0075)
2022Novo Nordisk Foundation annual report lists Altasciences Group as related party
FY2023USDA annual reports show 1,931 dogs across three facilities, exceeding stated capacity
Oct 2024Official USDA Warning Notice issued to Altasciences Preclinical Seattle LLC
Feb 2026Marie-Hélène Raigneau appointed CEO; Chris Perkin becomes executive chair

Open Data Gaps

Data Gap
  • No public beagle retirement or adoption program page; no quantitative rehoming outcomes disclosed
  • No breed-mix disclosure for canine colonies (beagle proportion vs. other strains unknown)
  • Canine supplier identity undisclosed; alleged breeder linkages require document verification
  • Novo Nordisk client relationship with Altasciences: not confirmed, not denied
  • Complete USDA enforcement history requires additional FOIA beyond publicly posted records
  • Revenue, study volume, and per-facility animal throughput figures are not publicly reported

Sources & References

  • USDA APHIS: Annual reports (Form 7023) for certificates 43-R-0122, 91-R-0075, 23-R-0107; Official Warning Notice (Oct 2024); FOIA enforcement logs
  • Novo Nordisk Foundation: 2022 Annual Report; consolidated financial statements listing related parties and ownership percentages
  • Novo Holdings A/S: Investment portfolio disclosures; Altasciences acquisition announcement (Mar 2021)
  • Altasciences: Corporate website; published literature referencing “conscious beagles” in CV telemetry; leadership announcements (Feb 2026)
  • SNBL/Shin Nippon: Historical USDA registrations (91-R-0053, 91-B-0078); entity transfer documentation
  • Industry reporting: PE transaction coverage (Audax, Kilmer); local journalism on Everett campus acquisition

Last updated: March 2026. This profile is based on publicly available records and does not include information obtained through confidential sources. Corrections and additions are welcome.