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Contract Research Organizations

CROs are the companies that test drugs on beagles. The pharmaceutical company designs the drug. The CRO houses the animals, employs the technicians, runs the studies, delivers the data — and kills the dogs. This structural separation allows pharma companies to state, accurately, that they do not conduct animal testing. They contract it out.

5
major CROs profiled
Global operations
$8B+
combined revenue
Preclinical segments
15,000+
dogs across CROs
USDA-reported
0
name beagles in filings
All report 'dogs'
Key Finding
The pharmaceutical company's name never appears on the facility door where dogs are gavaged, bled, and euthanized. CROs exist to provide that distance. They also provide regulatory expertise, economies of scale, and — crucially — deniability.

Dogs Reported by CRO (USDA Data)

Most recent available USDA annual report data per registration

These are the only publicly available dog counts for CROs. No CRO discloses beagle-specific numbers. The actual global total is higher — these are single-registration snapshots, not enterprise-wide counts.

Note: USDA reports 'dogs' not 'beagles.' SNBL transferred US operations to Altasciences ~2018. Inotiv/Envigo ceased Cumberland operations Sept 2022.

Source: USDA APHIS Form 7023 annual reports: Charles River FY2022 (14-R-0144), Labcorp FY2017 (35-R-0030), Altasciences FY2023 (3 certificates combined)

Charles River Laboratories

Major Global CRO

The world's largest CRO. 9,099 dogs in FY2022 USDA report. CEO transition underway. Elliott Investment Management holds board influence. $500M invested in '3Rs' and alternatives — while simultaneously reporting increased primate study demand.

Wilmington, MA$4.0BNYSE: CRL9,099 dogs

Labcorp Drug Development

Major Global CRO
formerly Covance

Formerly Covance — rebranded after the name became synonymous with animal testing protests. Madison, WI facility reported 4,226 dogs (FY2017). Corporate chain: Corning → Covance → Labcorp → Fortrea spinoff. Cardiovascular telemetry in beagles confirmed at Harrogate, UK.

Burlington, NC$2.9B (BLS)NYSE: LH4,226 dogs

Inotiv

Mid-Tier — Going Concern

Acquired Envigo for ~$657M. Within months, the Cumberland facility produced the largest AWA penalty in history ($35M). Stock collapsed from $53 to $0.33. Management reports 'substantial doubt about ability to continue as a going concern.' 16.6% of revenue from a single unnamed client.

West Lafayette, IN$513MNASDAQ: ISEE~5,000 (peak) dogs

SNBL (Shin Nippon Biomedical Labs)

Specialist CRO

Founded in 1957 as a dog center. Japanese-language papers confirm beagle toxicology studies. Also supplies beagles commercially. $185K USDA penalty for primate transport failures. Cambodia primate supply chain overlaps with DOJ's 'Operation Long-Tailed Liberation.'

Kagoshima, Japan~$215MTSE: 2395Undisclosed dogs

Altasciences

Mid-Tier — Novo-Owned

Largest disclosed canine colony among CROs: 1,931 dogs across 3 sites. 100% owned by Novo Holdings — a subsidiary of the Novo Nordisk Foundation, which controls Novo Nordisk (76.9% voting rights). Cardiovascular telemetry in conscious beagles confirmed in published literature.

Laval, Quebec~$340M (est.)Private (Novo Holdings)1,931 dogs

The Supply Chain

Pharma Company
Designs the drug
CRO
Tests it on beagles
Breeder (Marshall)
Supplies the dogs
Regulator (FDA)
Accepts the data